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Article

CSF chitinase 3-like-1 association with disability of primary progressive MS

2 Jul 2020

Abstract excerpt

Objective To assess the role of CSF chitinase 3-like-1 (CHI3L1), chitinase 3-like-2 (CHI3L2), and neurofilament light chain (NfL) in predicting the course of primary progressive MS (PPMS). Methods We analyzed CSF CHI3L1, CHI3L2, and NfL levels in 25 patients with PPMS with disease duration ≤10 years and no disease-modifying therapy for ≥6 months from the prospective Understanding Primary Progressive Multiple...

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PMID: 32611760
DOI: 10.1212/nxi.0000000000000815

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