Article

Small peptide fingerprint (peptidomics) of Amyotrophic Lateral Sclerosis in CSF

2023-12-14

Abstract excerpt

<h4>Background</h4> Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by abnormal protein aggregates in motor neurons. Present and earlier proteomic studies to characterize peptides in cerebrospinal fluid (CSF) associated with motoneuron pathology did not target the low molecular weight proteins and peptides. We generated the hypothesis that specific changes in CSF peptides or low mo...

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Literature Corpus work: 154f5b90-162e-5801-8d58-a25163cbd3de
DOI: 10.1101/2023.12.14.23299946

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