Article

A primate-specific (GCC) repeat in SMAD9 undergoes natural selection in humans and harbors unambiguous genotypes in late-onset neurocognitive disorder.

2022-10-17

Abstract excerpt

<title>Abstract</title> <p>Across numerous primate species and tissues, <italic>SMAD9</italic> (SMAD Family Member 9) reaches the highest level of expression in the human brain. This gene contains a (GCC) short tandem repeat (STR) at the interval between + 1 and + 60 of the transcription start site, which is in the 1st percent of high-ranking (GCC)-repeats in respect of length. Here we sequenced this (GCC)-repeat...

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Literature Corpus work: 816109e7-9f64-5f4f-af43-1b0ca2b44c48
DOI: 10.21203/rs.3.rs-2144796/v1

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