Back to search

Article

A primate-specific (CCG) repeat in DISP2 is subject to natural selection in human and harbors divergent genotypes in late-onset neurocognitive disorder.

2023-06-01

Abstract excerpt

<title>Abstract</title> <p>(CCG)-repeats are predominantly enriched in genic regions, mutation hotspots for C to T truncating substitutions, and involved in various neurological and neurodevelopmental disorders. However, intact blocks of this class of STRs are widely overlooked with respect to their link with natural selection. The human <italic>DISP2</italic> (dispatched RND transporter family member 2) has the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
41e1379b-532d-55f5-8c65-a42845f88adc
DOI
10.21203/rs.3.rs-2991406/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A primate-specific (CCG) repeat in DISP2 is subject to natural selection in human and harbors divergent genotypes in late-onset neurocognitive disorder.DOI 10.21203/rs.3.rs-2991406/v1
A primate-specific (CCG) repeat in DISP2 is subject to natural selection in human and harbors unambiguous genotypes in late-onset neurocognitive disorderSemantic proximity
A Hypermutable Region in the DISP2 Gene Links to Natural Selection and Late-Onset Neurocognitive Disorders in Humans.Semantic proximity
Natural selection at the RASGEF1C (GGC) repeat in human and divergent genotypes in late-onset neurocognitive disorder.Semantic proximity
Natural selection at the RASGEF1C (GGC) repeat in human and divergent genotypes in late-onset neurocognitive disorder.Semantic proximity
Natural Selection at an Exceptionally Long GGC Repeat in the Human RASGEF1C and Divergent Genotypes in Late-onset Neurocognitive DisorderSemantic proximity
A primate-specific (GCC) repeat in SMAD9 undergoes natural selection in humans and harbors unambiguous genotypes in late-onset neurocognitive disorder.Semantic proximity
A primate-specific (GCC) repeat in the untranslated region of SMAD9 undergoes natural selection and links with late-onset neurocognitive disorder in humanSemantic proximity
A (GCC) Repeat in the Untranslated Region of Human SBF1 Departs from Hardy-Weinberg Equilibrium in Human and Links to Late-onset Neurocognitive Disorder.Semantic proximity
A (GCC) repeat in SBF1 reveals a novel biological phenomenon in human and links to late onset neurocognitive disorder.Semantic proximity
A GCC repeat in RAB26 undergoes natural selection in human and harbors divergent genotypes in late-onset Alzheimer's disease.Semantic proximity
Natural Selection at the NHLH2 Core Promoter Exceptionally Long CA-Repeat in Human and Disease-Only Genotypes in Late-Onset Neurocognitive Disorder.Semantic proximity
Computational and experimental hunt for expansion prone tandem CNG repeats in human genomesSemantic proximity
Select a neighboring publication to make it the new centre.