Article

A primate-specific (GCC) repeat in the untranslated region of SMAD9 undergoes natural selection and links with late-onset neurocognitive disorder in human

2022-04-26

Abstract excerpt

Across numerous primate species and tissues, SMAD9 (SMAD Family Member 9) gene, reaches the highest level of expression in the human brain. This gene contains a short tandem repeat (STR) of (GCC) motifs at the interval between +1 and +60 of the transcription start site (ENST00000379826.5 SMAD9-202), which is in the 1st percent of high-ranking (GCC)-repeats in respect of length. Here we sequenced this (GCC)-repeat...

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Literature Corpus work: 5e505b12-ed06-5bd0-afb2-49626c07a628
DOI: 10.21203/rs.3.rs-1565676/v1

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