Article

A (GCC) Repeat in the Untranslated Region of Human SBF1 Departs from Hardy-Weinberg Equilibrium in Human and Links to Late-onset Neurocognitive Disorder.

2022-01-13

Abstract excerpt

The human SBF1 (SET binding factor 1) gene, alternatively known as MTMR5 , is predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset neurocognitive disorders (NCDs), such as Alzheimer’s disease. This gene contains a (GCC)-repeat at the interval between +1 and +60 of the transcription start site (SBF1-202 ENST00000380817.8). Sequencing of the SBF1 (GCC)-repeat in a sample of...

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Literature Corpus work: 62c4c995-915a-5c93-91f1-3f3d41857671
DOI: 10.21203/rs.3.rs-1240759/v1

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