Article

IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity

2022-03-12

Abstract excerpt

Besides anti-viral functions, Type I IFN expresses potent anti-inflammatory properties and is being widely used to treat certain autoimmune conditions, such as multiple sclerosis (MS). In murine model of MS, experimental autoimmune encephalomyelitis (EAE), administration of IFNβ effectively attenuates the disease development. However, the precise mechanisms underlying the treatment remain elusive. In this study, w...

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Literature Corpus work: 815d4170-a5a1-5c5b-966a-d912d544d03b
DOI: 10.1101/2022.03.11.483954

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