Article

Ifi27l2a acts as a cytokine that promotes a pro-inflammatory phenotype in microglia and enhances neuroinflammation

2025-09-24

Abstract excerpt

<title>Abstract</title> <p>Interferon alpha-inducible protein 27 like 2A (<italic>Ifi27l2a</italic>) was initially identified as an interferon-stimulated gene (Isg) involved in host-dependent mechanisms during viral invasion. We have recently shown that the Ifi27l2a protein also plays a critical role in microglia and the spreading of neuroinflammation. However, the detailed mechanisms of action of intracellular a...

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Literature Corpus work: 3050c31d-cde7-5378-9c5d-65247fd6f950
DOI: 10.21203/rs.3.rs-7383703/v1

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