Article

In BRCA1 and BRCA2 Breast Cancers, Chromosome Breaks Occur Near Herpes Tumor Virus Sequences

2021-05-20

Abstract excerpt

Inherited mutations in BRCA1 and BRCA2 genes increase risks for breast, ovarian, and other cancers. Both genes encode proteins for accurately repairing chromosome breaks. If mutations inactivate this function, chromosome fragments may not be restored correctly. Resulting chromosome rearrangements can become critical breast cancer drivers. Because I had data from thousands of cancer structural alterations that matc...

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Literature Corpus work: 617c13ae-0ba6-5c63-a3b6-569609ecba3e
DOI: 10.20944/preprints202105.0490.v1

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