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Article

Mitochondrial ALDH2 Deficiency as an Oxidative Stress

2004-04-01

Abstract excerpt

A bstract : Mitochondrial aldehyde dehydrogenase 2 (ALDH2) plays a major role in ethanol metabolism. It is involved in acetaldehyde detoxification. A polymorphism of the ALDH2 gene is specific to North‐East Asians. Sensitivity to ethanol is highly associated with this polymorphism ( ALDH2*2 allele), which is responsible for a deficiency of ALDH2 activity. We first show that this deficiency influences the risk for...

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Literature Corpus work
81450965-fbb2-5310-8740-d10293e86ebc
DOI
10.1196/annals.1293.004
Open publication

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Mitochondrial ALDH2 Deficiency as an Oxidative StressDOI 10.1196/annals.1293.004
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