Article

Distinctive Whole-brain Cell Types Predict Tissue Damage Patterns in Thirteen Neurodegenerative Conditions

2023-06-09

Abstract excerpt

For over a century, brain research narrative has mainly centered on neuron cells. Accordingly, most neurodegenerative studies focus on neuronal dysfunction and their selective vulnerability, while we lack comprehensive analyses of other major cell types’ contribution. By unifying spatial gene expression, structural MRI, and cell deconvolution, here we describe how the human brain distribution of canonical cell typ...

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Literature Corpus work: 74e61816-0c9c-5291-a8ea-73f8e178b1b4
DOI: 10.1101/2023.06.08.544227

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