Article

Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals novel associations with AD pathology

2024-04-27

Abstract excerpt

Alzheimer’s disease (AD) is a neurodegenerative disorder with complex pathological manifestations and is the leading cause of cognitive decline and dementia in elderly individuals. A major goal in AD research is to identify new therapeutic pathways by studying the molecular and cellular changes in the disease, either downstream or upstream of the pathological hallmarks. In this study, we present a comprehensive in...

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Literature Corpus work: 8a015815-e19a-5ef1-9e4e-c8ebff4828d2
DOI: 10.1101/2024.04.23.590816

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