Article

Modern human alleles differentially regulate gene expression across brain regions: implications for brain evolution

2019-09-18

Abstract excerpt

The availability of high-coverage genomes of our extinct relatives, the Neanderthals and Denisovans, and the emergence of large, tissue-specific databases of modern human genetic variation, offer the possibility of probing the evolutionary trajectory of heterogenous structures of great interest, such as the brain. Using the GTEx cis-eQTL dataset and an extended catalog of Homo sapiens -specific alleles relative t...

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Literature Corpus work: 80f0bacd-232a-5928-9472-15ce908123bf
DOI: 10.1101/771816

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