Article

Evaluation of the gene fusion landscape in early onset sporadic rectal cancer reveals association with chromatin architecture and genome stability

2024-04-12

Abstract excerpt

Gene fusions represent a distinct class of structural variants identified frequently in cancer genomes across cancer types. Several gene fusions exhibit gain of oncogenic function and thus have been the focus of development of efficient targeted therapies. However, investigation of fusion landscape in early-onset sporadic rectal cancer, a poorly studied colorectal cancer subtype prevalent in developing countries,...

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Literature Corpus work: 80caafda-9c66-5692-8b40-5ca5861d11e4
DOI: 10.1101/2024.04.09.588655

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Evaluation of the gene fusion landscape in early onset sporadic rectal cancer reveals association with chromatin architecture and genome stabilityDOI 10.1101/2024.04.09.588655Read

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