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Integrative analysis of oncogenic fusion genes and their functional impact in colorectal cancer

27 Jun 2018

Abstract excerpt

BACKGROUND: Fusion genes are good candidates of molecular targets for cancer therapy. However, there is insufficient research on the clinical implications and functional characteristics of fusion genes in colorectal cancer (CRC). METHODS: In this study, we analysed RNA sequencing data of CRC patients (147 tumour and 47 matched normal tissues) to identify oncogenic fusion genes and evaluated their role in CRC....

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PMID: 29955133
DOI: 10.1038/s41416-018-0153-3

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