Article

Mouse models of immune dysfunction: Their neuroanatomical differences reflect their anxiety-behavioural phenotype

2021-06-15

Abstract excerpt

Extensive evidence supports the role of the immune system in modulating brain function and behaviour. However, past studies have revealed striking heterogeneity in behavioural phenotypes produced from immune system dysfunction. Using magnetic resonance imaging (MRI), we studied the neuroanatomical differences among 11 distinct genetically-modified mouse lines (n=371), each deficient in a different element of the i...

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Literature Corpus work: 80bf0da3-27d0-599c-af3d-47dc97b638ab
DOI: 10.1101/2021.06.14.448406

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