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Article

Testing associations between human anxiety and genes previously implicated by mouse anxiety models.

Genes, brain, and behavior - 1 Dec 2023

Brasher Maizy S, Mize Travis J, Thomas Aimee L, Hoeffer Charles A, Ehringer Marissa A, Evans Luke M

Abstract excerpt

Anxiety disorders are common and can be debilitating, with effective treatments remaining hampered by an incomplete understanding of the underlying genetic etiology. Improvements have been made in understanding the genetic influences on mouse behavioral models of anxiety, yet it is unclear the extent to which genes identified in these experimental systems contribute to genetic variation in human anxiety...

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Identifiers

PMID: 37259642
DOI: 10.1111/gbb.12851
PMCID: PMC10733569

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