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Article

Genetic variations and their interaction with thirdhand smoke exposure on anxiety and memory in Collaborative Cross mice.

Environment international - 1 Apr 2026

Yao Yiyan, Wang Dawei, Wang Pin, Ton Ethan, Schick Suzaynn F, Jacob Peyton, Tang Xiaochen, Destaillats Hugo, Hang Bo, Snijders Antoine M, Mao Jian-Hua, Inman Jamie L, Chang Hang

Abstract excerpt

Thirdhand smoke (THS) is linked to adverse health effects, but the effect of genetic variations on behavioral outcomes is poorly understood. To investigate this, we assessed anxiety- and memory-related behaviors in 820 mice from 21 strains of the genetically diverse Collaborative Cross (CC) mouse that were exposed to THS from 4 through 10 weeks of age. Anxiety was evaluated with a light/dark box assay with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41855708
DOI: 10.1016/j.envint.2026.110197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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