Article
Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Apr 2005
Krömer Simone A, Kessler Melanie S, Milfay Dale, Birg Isabel N, Bunck Mirjam, Czibere Ludwig, Panhuysen Markus, Pütz Benno, Deussing Jan M, Holsboer Florian, Landgraf Rainer, Turck Christoph W
Abstract excerpt
For >15 generations, CD1 mice have been selectively and bidirectionally bred for either high-anxiety-related behavior (HAB-M) or low-anxiety-related behavior (LAB-M) on the elevated plus-maze. Independent of gender, HAB-M were more anxious than LAB-M animals in a variety of additional tests, including those reflecting risk assessment behaviors and ultrasound vocalization, with unselected CD1 "normal" control...
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