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Article

Traits of fear resistance and susceptibility in an advanced intercross line.

The European journal of neuroscience - 1 Nov 2013

McGuire Jennifer L, Bergstrom Hadley C, Parker Clarissa C, Le Thien, Morgan Maria, Tang Haiying, Selwyn Reed G, Silva Afonso C, Choi Kwang, Ursano Robert J, Palmer Abraham A, Johnson Luke R

Abstract excerpt

Genetic variability in the strength and precision of fear memory is hypothesised to contribute to the etiology of anxiety disorders, including post-traumatic stress disorder. We generated fear-susceptible (F-S) or fear-resistant (F-R) phenotypes from an F8 advanced intercross line (AIL) of C57BL/6J and DBA/2J inbred mice by selective breeding. We identified specific traits underlying individual variability in...

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PMID: 23968228
DOI: 10.1111/ejn.12337
PMCID: PMC5581004

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CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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