Article

MVMRmode: Introducing an R package for plurality valid estimators for multivariable Mendelian randomisation

2023-01-11

Abstract excerpt

<h4>Background</h4> Mendelian randomisation (MR) is the use of genetic variants as instrumental variables. Mode-based estimators (MBE) are one of the most popular types of estimators used in univariable-MR studies. However, because there are no plurality valid regression estimators, there are no existent modal estimators for multivariable-MR. <h4>Methods</h4> We use the residual method for multivariable-MR to intr...

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Literature Corpus work: 80b48ad5-7a4f-5cdf-962f-af0ff4c89c0d
DOI: 10.1101/2023.01.09.23284345

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