Article

A Comparison Of Robust Mendelian Randomization Methods Using Summary Data

2019-03-15

Abstract excerpt

The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain more precise estimates of causal effects. Since it is unlikely that all genetic variants will be valid instrumental variables, several robust methods have been proposed. We compare nine robust methods for Mend...

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Literature Corpus work: 655b1a5e-1ce0-51ae-82bb-2e1a3198c691
DOI: 10.1101/577940

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