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Article

MVMRmode: Introducing an R package for plurality valid estimators for multivariable Mendelian randomisation.

PloS one - 1 Jan 2024

Woolf Benjamin, Gill Dipender, Grant Andrew J, Burgess Stephen

Abstract excerpt

BACKGROUND: Mendelian randomisation (MR) is the use of genetic variants as instrumental variables. Mode-based estimators (MBE) are one of the most popular types of estimators used in univariable-MR studies and is often used as a sensitivity analysis for pleiotropy. However, because there are no plurality valid regression estimators, modal estimators for multivariable-MR have been under-explored. METHODS: We use...

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Identifiers

PMID: 38713711
DOI: 10.1371/journal.pone.0291183
PMCID: PMC11075861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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