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Cell-free RNA reveals host and microbial correlates of broadly neutralizing antibody development against HIV

2025-06-14

Abstract excerpt

A small number of people living with HIV (PLWH) develop broadly neutralizing antibodies (bNAbs) targeting multiple HIV strains. Although several viral and immune factors contribute to bNAb development, the genetic and environmental factors driving this response remain largely unknown. We performed combined cell-free DNA (cfDNA) and cell-free RNA (cfRNA) sequencing in 42 plasma samples from a longitudinal cohort of...

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Literature Corpus work
8050b4d6-a29c-526d-afc8-14849784c0df
DOI
10.1101/2025.06.10.658831
Open publication

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Cell-free RNA reveals host and microbial correlates of broadly neutralizing antibody development against HIVDOI 10.1101/2025.06.10.658831
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