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Alterations of the gut microbiome in HIV infection highlight human anelloviruses as potential predictors of immune recovery

17 Oct 2024

Abstract excerpt

BACKGROUND: HIV-1 infection is characterized by a massive depletion of mucosal CD4 T cells that triggers a cascade of events ultimately linking gut microbial dysbiosis to HIV-1 disease progression and pathogenesis. The association between HIV infection and the enteric virome composition is less characterized, although viruses are an essential component of the gut ecosystem. Here, we performed a cross-sectional...

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PMID: 39420423
DOI: 10.1186/s40168-024-01925-7

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