Article

Blood-brain barrier model architecture shapes peripheral immune cell trafficking in Parkinson’s disease

2026-06-09

Abstract excerpt

Parkinson’s disease (PD) is a neurodegenerative disorder traditionally characterized by dopaminergic neuron loss in the substantial nigra pars compacta , but peripheral immune dysregulation and blood-brain barrier (BBB) dysfunction have been increasingly implicated in disease etiology. However, how circulating immune cells interact with the human BBB and how these interactions are captured across experimental mod...

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Literature Corpus work: 80132413-71a4-5c2c-8b04-e5d550776879
DOI: 10.64898/2026.06.04.730214

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