Article

Parkinson’s disease risk factors are expressed at brain barriers

2025-10-21

Abstract excerpt

Parkinson’s disease (PD) is characterized by the selective loss of dopaminergic neurons in the substantia nigra pars compacta , but whether its etiology is cell autonomous remains unclear. Increasing evidence implicates the blood-central nervous system (CNS) barriers in disease development, highlighting the importance of identifying genetic risk factors linked to cells forming the cerebrovasculature to advance th...

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Literature Corpus work: 314009a9-a533-57ff-bc9a-d768ab25d84c
DOI: 10.1101/2025.10.20.683561

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