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The restricted N-glycome of neurons is programmed during differentiation

2024-10-17

Abstract excerpt

The protein glycome of individual cell types in the brain is unexplored, despite the critical function of these modifications in development and disease. In aggregate, the most abundant asparagine (N-) linked glycans in the adult brain are high mannose structures, and specifically Man 5 GlcNAc 2 (Man-5), which normally exits the ER for further processing in the Golgi. Mannose structures are uncommon in other org...

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Literature Corpus work
7f64b5dd-432f-5109-b948-70584b6a4804
DOI
10.1101/2024.10.15.618477
Open publication

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The restricted N-glycome of neurons is programmed during differentiationDOI 10.1101/2024.10.15.618477
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