Article

Unique N-glycosylation signatures in Aβ oligomer- and lipopolysaccharide-activated human iPSC-derived microglia

2024-11-19

Abstract excerpt

<title>Abstract</title> <p>Microglia are the immune cells in the central nervous system (CNS) and become pro-inflammatory/activated in Alzheimer’s disease (AD). Cell surface glycosylation plays an important role in immune cells; however, the N-glycosylation and glycosphingolipid (GSL) signatures of activated microglia are poorly understood. Here, we study comprehensive combined transcriptomic and glycomic profile...

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Literature Corpus work: 7e97a38b-ffc1-5cf1-8b6d-27be5deb8516
DOI: 10.21203/rs.3.rs-5308977/v1

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