Article

Multi-omic analysis of guided and unguided forebrain organoids reveal differences in cellular composition and metabolic profiles

2023-12-23

Abstract excerpt

Neural organoids are invaluable model systems for studying neurodevelopment and neurological diseases. For this purpose, reproducible differentiation protocols are needed that minimize inter-organoid variability whilst generating neural organoids that physiologically resemble the brain area of interest. Currently, two main approaches are used: guided, where the differentiation towards neuroectoderm and subsequentl...

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Literature Corpus work: 3061b843-21c1-5bbb-bd2f-12be7c0e32a7
DOI: 10.1101/2023.12.21.572871

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