Article

Effective imaging and treatment of Acute Myeloid Leukemia with radiotheranostics targeting the activated conformation of integrin-β2

2025-10-29

Abstract excerpt

<title>Abstract</title> <p>There remains an unmet clinical need for improved treatment strategies in Acute Myeloid Leukemia (AML). Although radiopharmaceutical therapies targeting non-cancer-selective antigens have shown promise in AML, their clinical utility is often limited by prolonged bone marrow suppression. Using a unique proteomics-based strategy, we recently identified the active conformation of integrin-...

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Literature Corpus work: 7f09802c-29b7-58f7-853a-d993bb004459
DOI: 10.21203/rs.3.rs-7796168/v1

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