Article

Identification of Glycerol 3-phosphate acyltransferase as a potent modifier of α-Synuclein-induced toxicity

2024-04-09

Abstract excerpt

<title>Abstract</title> <p> Although multiple cellular pathways have been implicated in a-Synuclein (a-syn)-associated Parkinson’s disease (PD), the role of lipid metabolism remains elusive. Using the <italic>Drosophila</italic> system as a genetic screening tool, we identified <italic>mino</italic> , which encodes the mitochondrial isoform of the lipid synthesis enzyme glycerol 3-phosphate acyltransferase (...

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Literature Corpus work: 7f0302d5-1adc-536c-aa4c-f985c0f6a29f
DOI: 10.21203/rs.3.rs-4199316/v1

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