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Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's disease

2023-09-26

Abstract excerpt

<title>Abstract</title> <p>Clinical trials have demonstrated the potential neuroprotective effects of uric acid in Alzheimer's disease. However, the specific mechanism underlying the neuroprotective effect of uric acid remains unclear. In the present study, we investigated the neuroprotective effect and underlying mechanism of uric acid in Alzheimer's disease mouse models. Various behavioral tests including eleva...

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Literature Corpus work
7ef2563c-41b4-5e9c-b0ad-8b4314898733
DOI
10.21203/rs.3.rs-3355003/v1
Open publication

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Uric acid mitigates cognitive deficits via transcription factor EB - mediated microglial autophagy in mice models of Alzheimer's diseaseDOI 10.21203/rs.3.rs-3355003/v1
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