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Article

Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer’s disease

2022-10-03

Abstract excerpt

<title>Abstract</title> <p>In recent years, a burgeoning body of evidence has pointed to age-related dysfunction in neuronal autophagy as playing a prominent role in neuropathology associated with Alzheimer’s disease (AD). In the present study, we investigated the effects of urolithin A (UA), a metabolite generated from ellagic acid via its metabolism by gut bacteria, as an autophagy activator with potential neur...

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Literature Corpus work
e688ee33-e95e-52ed-a75b-5b90f2a4e454
DOI
10.21203/rs.3.rs-2046848/v2
Open publication

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Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer’s diseaseDOI 10.21203/rs.3.rs-2046848/v2
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