Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic Potential of Vital Transcription Factors in Alzheimer’s and Parkinson’s Disease With Particular Emphasis on Transcription Factor EB Mediated Autophagy

14 Dec 2021

Abstract excerpt

Autophagy is an important cellular self-digestion and recycling pathway that helps in maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and endolysosomal pathway has been reported in several neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington disease (HD) and is cited as a critically important feature for central nervous system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Endoplasmic Reticulum Stress and Disease
Share to Nuclear Receptors and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34970114
DOI: 10.3389/fnins.2021.777347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic Potential of Vital Transcription Factors in Alzheimer’s and Parkinson’s Disease With Particular Emphasis on Transcription Factor EB Mediated AutophagyPMID 34970114Read ↗

Novel Insight into Functions of Transcription Factor EB (TFEB) in Alzheimer’s Disease and Parkinson’s DiseaseSemantic proximity Read ↗

TFEB in Alzheimer's disease: From molecular mechanisms to therapeutic implicationsSemantic proximity Read ↗

The regulatory mechanism and therapeutic potential of transcription factor <scp>EB</scp> in neurodegenerative diseasesSemantic proximity Read ↗

TFEB Biology and Agonists at a GlanceSemantic proximity Read ↗

From the regulatory mechanism of TFEB to its therapeutic implicationsSemantic proximity Read ↗

Role of TFEB in Huntington’s DiseaseSemantic proximity Read ↗

TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: Molecular mechanisms, cellular processes, and emerging therapeutic opportunitiesSemantic proximity Read ↗

TFEB acetylation promotes lysosome biogenesis and ameliorates Alzheimer's disease-relevant phenotypes in mice.Semantic proximity Read ↗

Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-SynucleinSemantic proximity Read ↗

Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseasesSemantic proximity Read ↗

TFEB is a central regulator of the aging process and age-related diseasesSemantic proximity Read ↗

The Role and Regulatory Mechanism of Transcription Factor EB in Health and DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.