Article

Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals

2017-07-20

Abstract excerpt

Eukaryotic genomes must accomplish the tradeoff between compact packaging for genome stability and inheritance, and accessibility for gene expression. They do so using post-translational modifications of four ancient canonical histone proteins (H2A, H2B, H3 and H4), and by deploying histone variants with specialized chromatin functions. While some histone variants are highly conserved across eukaryotes, others car...

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Literature Corpus work: 7ecf761f-de76-5fb0-a056-ea9690b39cc2
DOI: 10.1101/165936

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