Article
Histone variants and epigenetics.
Cold Spring Harbor perspectives in biology - 5 Jan 2015
Henikoff Steven, Smith M Mitchell
Abstract excerpt
Histones package and compact DNA by assembling into nucleosome core particles. Most histones are synthesized at S phase for rapid deposition behind replication forks. In addition, the replacement of histones deposited during S phase by variants that can be deposited independently of replication provide the most fundamental level of chromatin differentiation. Alternative mechanisms for depositing different...
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