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Article

Short Histone H2A Variants: Small in Stature but not in Function.

Cells - 2 Apr 2020

Jiang Xuanzhao, Soboleva Tatiana A, Tremethick David J

Abstract excerpt

The dynamic packaging of DNA into chromatin regulates all aspects of genome function by altering the accessibility of DNA and by providing docking pads to proteins that copy, repair and express the genome. Different epigenetic-based mechanisms have been described that alter the way DNA is organised into chromatin, but one fundamental mechanism alters the biochemical composition of a nucleosome by substituting one...

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PMID: 32252453
DOI: 10.3390/cells9040867
PMCID: PMC7226823

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Source receipt: pubmed, retrieved 7 Sept 2026.

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