Article
Histone variant innovation in a rapidly evolving chordate lineage.
BMC evolutionary biology - 15 Jul 2011
Moosmann Alexandra, Campsteijn Coen, Jansen Pascal Wtc, Nasrallah Carole, Raasholm Martina, Stunnenberg Henk G, Thompson Eric M
Abstract excerpt
BACKGROUND: Histone variants alter the composition of nucleosomes and play crucial roles in transcription, chromosome segregation, DNA repair, and sperm compaction. Modification of metazoan histone variant lineages occurs on a background of genome architecture that shows global similarities from sponges to vertebrates, but the urochordate, Oikopleura dioica, a member of the sister group to vertebrates, exhibits...
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