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sCLC: a Clustering Linear Combination (CLC) Method for Multiple Phenotype Association Studies Based on GWAS Summary Statistics

2022-11-25

Abstract excerpt

There is strong evidence showing that joint analysis of multiple phenotypes in genome-wide association studies (GWAS) can increase statistical power when detecting the association between genetic variants and human complex diseases. We previously developed the Clustering Linear Combination (CLC) method and a computationally efficient CLC (ceCLC) method to test the association between multiple phenotypes and a gene...

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Literature Corpus work
7ebe5c03-f758-5f71-ab08-2b172dfaae82
DOI
10.21203/rs.3.rs-2284388/v1
Open publication

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sCLC: a Clustering Linear Combination (CLC) Method for Multiple Phenotype Association Studies Based on GWAS Summary StatisticsDOI 10.21203/rs.3.rs-2284388/v1
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