Article
Youthful and age-related matreotypes predict drugs promoting longevity
2021-01-27
Abstract excerpt
The identification and validation of drugs that promote health during aging (‘geroprotectors’) is key to the retardation or prevention of chronic age-related diseases. Here we found that most of the established pro-longevity compounds shown to extend lifespan in model organisms also alter extracellular matrix gene expression ( i.e., matrisome) in human cell lines. To harness this novel observation, we used age-st...
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Identifiers and source
- Literature Corpus work
- 7e65354a-9561-53e6-aab9-2f0162538a22
- DOI
- 10.1101/2021.01.26.428242