Article
Using the drug-protein interactome to identify anti-ageing compounds for humans
2018-10-08
Abstract excerpt
Advancing age is the dominant risk factor for most of the major killer diseases in developed countries. Hence, ameliorating the effects of ageing may prevent multiple diseases simultaneously. Drugs licensed for human use against specific diseases have proved to be effective in extending lifespan and healthspan in animal models, suggesting that there is scope for drug repurposing in humans. New bioinformatic method...
Topics
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- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Coenzyme Q10 studies and effects
- Computational Drug Discovery Methods
- Dietary Effects on Health
- Genetics, Aging, and Longevity in Model Organisms
- Genomics, phytochemicals, and oxidative stress
- Sirtuins and Resveratrol in Medicine
Identifiers and source
- Literature Corpus work
- d06895e7-0c37-5635-a29b-3777a2e39933
- DOI
- 10.1101/438234