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Article

Extracellular Matrix Dynamics as an Emerging yet Understudied Hallmark of Aging and Longevity

1 Jan 2023

Abstract excerpt

The biomechanical properties of extracellular matrices (ECM) and their consequences for cellular homeostasis have recently emerged as a driver of aging. Here we review the age-dependent deterioration of ECM in the context of our current understanding of the aging processes. We discuss the reciprocal interactions of longevity interventions with ECM remodeling. And the relevance of ECM dynamics captured by the...

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PMID: 37191434
DOI: 10.14336/ad.2022.1116

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