Article

Transcriptomics-based screening identifies pharmacological inhibition of Hsp90 as a means to defer aging

2018-11-14

Abstract excerpt

<h4>Summary</h4> Aging is a major risk factor for human morbidity and mortality. Thus, the identification of compounds that defer aging, also known as ‘geroprotectors’, could greatly improve our health and promote a longer life. Here we screened for geroprotectors, employing the power of human transcriptomics to predict biological age. We used age-stratified human tissue transcriptomes to generate machine-learnin...

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Literature Corpus work: a5224154-0c59-50eb-9875-0c727fa3a8f0
DOI: 10.1101/468819

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