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Article

Six drivers of aging identified among genes differentially expressed with age

2024-08-06

Abstract excerpt

Many studies have compared gene expression in young and old samples to gain insights on aging, the primary risk factor for most major chronic diseases. However, these studies only describe associations, failing to distinguish drivers of aging from compensatory geroprotective responses and incidental downstream effects. Here, we introduce a workflow to characterize the causal effects of differentially expressed gen...

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Identifiers and source

Literature Corpus work
4845187d-de36-5a15-ae45-24b2737c5008
DOI
10.1101/2024.08.02.606402
Open publication

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Six drivers of aging identified among genes differentially expressed with ageDOI 10.1101/2024.08.02.606402
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