Article

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

2023-04-04

Abstract excerpt

Knowledge of locations and activities of cis -regulatory elements (CREs) is needed to decipher basic mechanisms of gene regulation and to understand the impact of genetic variants on complex traits. Previous studies identified candidate CREs (cCREs) using epigenetic features in one species, making comparisons difficult between species. In contrast, we conducted an interspecies study defining epigenetic states and...

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Literature Corpus work: 89928727-1d82-5727-a9dd-898699e2fb2b
DOI: 10.1101/2023.04.02.535219

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