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Article

Non-coding variants impact cis-regulatory coordination in a cell type-specific manner.

Genome biology - 18 Jul 2024

Pushkarev Olga, van Mierlo Guido, Kribelbauer Judith Franziska, Saelens Wouter, Gardeux Vincent, Deplancke Bart

Abstract excerpt

BACKGROUND: Interactions among cis-regulatory elements (CREs) play a crucial role in gene regulation. Various approaches have been developed to map these interactions genome-wide, including those relying on interindividual epigenomic variation to identify groups of covariable regulatory elements, referred to as chromatin modules (CMs). While CM mapping allows to investigate the relationship between chromatin...

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Identifiers

PMID: 39026229
DOI: 10.1186/s13059-024-03333-4
PMCID: PMC11256678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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