Article

Genome Scale Epigenetic Profiling Reveals Five Distinct Subtypes of Colorectal Cancer

2018-08-22

Abstract excerpt

<h4>BACKGROUND:</h4> Colorectal cancer is an epigenetically heterogeneous disease, however the extent and spectrum of the CpG Island Methylator Phenotype (CIMP) is not clear. <h4>RESULTS</h4> An unselected cohort of 216 colorectal cancers clustered into five clinically and molecularly distinct subgroups using Illumina 450K DNA methylation arrays. CIMP-High cancers were most frequent in the proximal colons of fem...

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Literature Corpus work: 7e499337-591d-5697-bdea-dfd90bbdc68e
DOI: 10.1101/397620

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