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Article

Genome-wide methylation analysis identifies a core set of hypermethylated genes in CIMP-H colorectal cancer.

BMC cancer - 28 Mar 2017

McInnes Tyler, Zou Donghui, Rao Dasari S, Munro Francesca M, Phillips Vicky L, McCall John L, Black Michael A, Reeve Anthony E, Guilford Parry J

Abstract excerpt

BACKGROUND: Aberrant DNA methylation profiles are a characteristic of all known cancer types, epitomized by the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC). Hypermethylation has been observed at CpG islands throughout the genome, but it is unclear which factors determine whether an individual island becomes methylated in cancer. METHODS: DNA methylation in CRC was analysed using the Illumina...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28351398
DOI: 10.1186/s12885-017-3226-4
PMCID: PMC5371203

Genes

EYA4
TFPI2
TLX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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