Article

Integrated genomic and epigenetic profiling reveals RAS pathway as a key driver of odontogenic tumors

2025-09-17

Abstract excerpt

<h4>ABSTRACT</h4> Odontogenic tumors (OTs) are highly proliferative lesions with a low number of driving mutations, suggesting that concurrent alternative molecular mechanisms could support their extensive proliferation capacity. In this study, we analyzed 94 tissue samples from 79 patients with OTs and 15 healthy controls to explore their genetic and epigenetic alterations. Whole Exome Sequencing identified the...

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Literature Corpus work: 7e257fae-b602-5655-9126-3d3e746e081d
DOI: 10.1101/2025.09.09.675228

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